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Made completely of PTFE, this holder is unaffected by chemicals and contains no trace elements which could be released into the liquid being filtered. It is, therefore, extremely well suited for particle removal from samples and reagents for analytical methods, such as NMR samples. Another inexpensive filter holder is made of clear, autoclavable polycarbonate. The silicone gasket enables a leak-free filtration at pressures of up to 7 bar by simply screwing it together manually. Filter supports in the top and bottom parts allow filtration in either direction.